List of Cars that use E15 by Model Year: 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011
2011 marked the first year for factory-approved E15 fuel, with Mercedes-Benz wading into the market before any other auto manufacturer.
List of 2011 E15 Cars, Trucks, and SUVs – Factory Approved
| Year | Make | Model | Engine | Trans. | Drive | City | Hwy | Comb | Ethanol % |
| 2011 | Acura | MDX 4WD | NA 3.7L 6 cyl. | Auto (S6) | AWD | 16 | 21 | 18 | 15 |
| 2011 | Mercedes-Benz | C 300 | NA 3L 6 cyl. | Manual (M6) | RWD | 18 | 26 | 21 | 15 |
| 2011 | Mercedes-Benz | CLS 550 | NA 5.5L 8 cyl. | Auto (A7) | RWD | 14 | 21 | 16 | 15 |
| 2011 | Mercedes-Benz | E 550 | NA 5.5L 8 cyl. | Auto (A7) | RWD | 15 | 23 | 18 | 15 |
E15 Cars by Model Year: 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011